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Wisconsin Team Reveals Way to Treat Drug-resistant Brain Tumor Cells Posted: 03 Jun 2012 07:12 AM PDT New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies. The study, from the brain-tumor research lab of Dr. John Kuo, assistant professor of neurological surgery and human oncology at UW School of Medicine and Public Health, also reports success for a combination therapy that knocks out signaling of multiple members of the epidermal growth factor receptor (EGFR) family in brain-cancer cells. read more

Free-electron lasers reveal detailed architecture of proteins Posted: 02 Jun 2012 10:32 AM PDT In the centennial year of Max von Laue’s discovery that X-ray diffraction can be used to unravel the atomic architecture of molecules, a new approach to the determination of high-resolution structures has been demonstrated. An international team of researchers has analyzed tiny protein crystals using short pulses of X-ray light from the world’s first hard X-ray free-electron laser, the US Department of Energy’s 300 million dollar Linac Coherent Light Source at Stanford. read more

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