ScienceDaily: Top Health News

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• Differences between human twins at birth highlight importance of intrauterine environment
• Disruption of cytoskeleton pathways contribute to amyotrophic lateral sclerosis pathogenesis
• Elegant delivery: Sophisticated technique for delivering multiple cancer treatments may solve frustrating hurdle for combinatorial drug therapies
• Critical cell in fighting E. coli infection identified

Differences between human twins at birth highlight importance of intrauterine environment Posted: 15 Jul 2012 04:38 PM PDT Your genes determine much about you, but environment can have a strong influence on your genes even before birth, with consequences that can last a lifetime. Scientists have for the first time shown that the environment experienced in the womb defines the newborn epigenetic profile, the chemical modifications to DNA we are born with, that could have implications for disease risk later in life.

Disruption of cytoskeleton pathways contribute to amyotrophic lateral sclerosis pathogenesis Posted: 15 Jul 2012 11:14 AM PDT A new genetic mutation that causes familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease, has been identified. Mutations to the profilin gene, which is essential to the growth and development of nerve cell axons, points to defects in a neuron's cytoskeleton structure as a potential common feature among diverse ALS genes.

Elegant delivery: Sophisticated technique for delivering multiple cancer treatments may solve frustrating hurdle for combinatorial drug therapies Posted: 15 Jul 2012 11:14 AM PDT Researchers have developed a novel system to simultaneously deliver a sustained dose of both an immune-system booster and a chemical to counter cancer's defensive secretions, resulting in a powerful therapy that, in mice, delayed tumor growth, sent tumors into remission and dramatically increased survival rates.

Critical cell in fighting E. coli infection identified Posted: 15 Jul 2012 11:13 AM PDT Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the world. But the research community is gaining ground. In a major new finding researchers have discovered a molecule's previously unknown role in fighting off E. coli and other bacterial infections, a discovery that could lead to new ways to protect people from these dangerous microorganisms.

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