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• Discovery opens up new areas of microbiology, evolutionary biology
• Global Regulator of mRNA Editing Found
• New approach prevents thrombosis without increasing the risk of bleeding
• MIT researchers design a microfluidic platform to see how cancer cells invade specific organs
• Pacific Salmon Inherit a Magnetic Sense of Direction
• Marker may predict response to ipilimumab in advanced melanoma

Discovery opens up new areas of microbiology, evolutionary biology Posted: 07 Feb 2014 07:30 AM PST A team of researchers led by Virginia Tech and University of California, Berkeley, scientists has discovered that a regulatory process that turns on photosynthesis in plants at daybreak likely developed on Earth in ancient microbes 2.5 billion years ago, long before oxygen became available. read more

Global Regulator of mRNA Editing Found Posted: 06 Feb 2014 12:07 PM PST An international team of researchers, led by scientists from the University of California, San Diego School of Medicine and Indiana University, have identified a protein that broadly regulates how genetic information transcribed from DNA to messenger RNA (mRNA) is processed and ultimately translated into the myriad of proteins necessary for life. read more

New approach prevents thrombosis without increasing the risk of bleeding Posted: 06 Feb 2014 11:55 AM PST In collaboration with an international team, researchers at Karolinska Institutet have developed an antibody, 3F7, which blocks a protein that is active in the coagulation system factor XII. Inhibition of factor XII makes it possible to prevent thrombosis in blood vessels without increasing the risk of bleeding in clinical settings. read more

MIT researchers design a microfluidic platform to see how cancer cells invade specific organs Posted: 06 Feb 2014 08:42 AM PST Nearly 70 percent of patients with advanced breast cancer experience skeletal metastasis, in which cancer cells migrate from a primary tumor into bone — a painful development that can cause fractures and spinal compression. While scientists are attempting to better understand metastasis in general, not much is known about how and why certain cancers spread to specific organs, such as bone, liver, and lungs. read more

Pacific Salmon Inherit a Magnetic Sense of Direction Posted: 06 Feb 2014 08:20 AM PST Even young hatchery salmon with no prior experience of the world outside will orient themselves according to the Earth's magnetic field in the direction of the marine feeding grounds frequented by their ancestors. These findings, reported in Current Biology, a Cell Press publication, on February 6th, suggest that Chinook salmon inherit a kind of built-in GPS that always points them home. read more

Marker may predict response to ipilimumab in advanced melanoma Posted: 06 Feb 2014 08:16 AM PST Among patients with advanced melanoma, presence of higher levels of the protein vascular endothelial growth factor (VEGF) in blood was associated with poor response to treatment with the immunotherapy ipilimumab, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research. The study suggests combining immunotherapy with VEGF inhibitors, also known as angiogenesis inhibitors, may be a potential option for these patients. read more

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