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- Search for Epigenetic Decoder in Brain Cells Leads Scientists to Rett Syndrome
- A new type of nerve cell found in the brain
- Scientists identify new genetic variants that influence insulin production
| Search for Epigenetic Decoder in Brain Cells Leads Scientists to Rett Syndrome Posted: 26 Dec 2012 06:46 AM PST A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a new analysis suggests that a regulatory protein called MeCP2, known for its involvement in the nervous system disorder Rett Syndrome, recognizes 5hmC in the brain and facilitates activation of the genes in which it is most abundant. |
| A new type of nerve cell found in the brain Posted: 26 Dec 2012 06:38 AM PST Scientists at Karolinska Institutet, in collaboration with colleagues in Germany and the Netherlands, have identified a previously unknown group of nerve cells in the brain. The nerve cells regulate cardiovascular functions such as heart rhythm and blood pressure. It is hoped that the discovery, which is published in the Journal of Clinical Investigation, will be significant in the long term in the treatment of cardiovascular diseases in humans. |
| Scientists identify new genetic variants that influence insulin production Posted: 25 Dec 2012 11:25 AM PST Scientists have found three new and relatively rare genetic variants that influence insulin production, offering new clues about the genetic factors behind diabetes. Insulin secretion has a crucial role in glucose homeostasis, and failure to secrete sufficient insulin is a hallmark of type 2 diabetes. |
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