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| Mystery of client selection of chaperone Hsp90 solved Posted: 07 Mar 2014 08:50 AM PST  Colleagues in Europe and America have solved the mystery of how one of the most important chaperone proteins in our cells, Hsp90, selects its client proteins. Hsp90 plays a role in nearly all processes in our cells, as well as in the origin of diseases such as Alzheimer disease, cancer and cystic fibrosis. Insight into the binding process of Hsp90 will increase our understanding of the origin of these diseases, thereby opening new avenues to prevent or cure them. The results of the research were published in Cell. |
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